Mechanisms of binaural remodeling in the forebrain
In the forebrain neural tuning to frequency contains more low frequencies than in the midbrain pathway. These low frequencies contribute large ITDs. Moreover, ITD tuning is asymmetric with respect to contra- und ipsilateral inputs (Figure). This transforms the code from a pure time code to a combined time and phase code. The mechanisms underlying this remodeling are not yet well understood. We are developing computational models based on experimental data with Prof. Führ for mathematics to better understand the underlying processes.
Most recent funding
DFG Wa606/21-1 (2011-2014)
Vonderschen K and Wagner H (2012) Transformation from a pure time delay to a mixed time and phase delay representation in the auditory forebrain pathway. J Neurosci 32: 5911-5923.
Vonderschen K and Wagner H (2009) Tuning to interaural time difference and frequency differs between the auditory arcopallium and the external nucleus of the inferior colliculus. J Neurophysiol 101: 2348-2361.