In this project we study how response variability changes when a) a stimulus is repeated many times and b) in the ascending auditory pathway. Christianson and Pena (J. Neurosci. 26: 5948, 2006) found that neural variability decreases from Nucleus laminaris to the central nucleus of the IC and that in IC two stimulus repetitions are enough for 90% of reliability. Since the responses in the external nucleus of the IC that receives input from the central nucleus are much lower than those in the central nucleus, we speculated that neural variability might increase again. This was indeed the case (Figure). We are currently investigating the precise mechanisms behind this increase in variability.
Kerstin Buelles (2012) Bachelor thesis